ʻO Orlistat (CAS NO.96829-58-2) kahi lāʻau i hoʻolālā ʻia e mālama i ka momona. Hoʻohana nui ʻia ia no ka pale ʻana i ka lawe ʻana o nā momona mai ka papaʻai kanaka, a laila hoʻoliʻiliʻi i ka lawe ʻana o ka calory. Ma waho aʻe, manaʻo ʻia ia no ka hoʻohana pū ʻana me kahi papa kauka hoʻoliʻiliʻi-hoʻoliʻiliʻi hoʻomalu ʻia.
| 'Ikamu | Nā Koina | Nā hopena hōʻike |
| Helehelena | ʻoiai i ka pauka pau | Pauka keʻokeʻo |
| ʻIʻike | Ka manawa paʻa o HPLC | Kūlike ʻole |
| Lae Melting | 42 ºC -45 ° C | 42 ° C-44 ° C |
| Hoʻololi ʻōnohi kikoʻī | -31.0 ° ~ -41.0 ° | -36.0 ° |
| Maʻemaʻe e HPLC | ʻaʻole emi ma lalo o 98.0% | 98.5% |
| Huina haumia | ʻaʻole ma mua o 2.0% | 1.6% |
| Max Kekahi haumia | ʻaʻole ma mua o 0.5% | 0.3% |
| Ka maʻi wai% (K & F) | ʻaʻole ma mua o 0.5% | 0,1% |
| Nā mea hoʻoheheʻe koena | EtOH ʻaʻole ʻoi aku ma mua o 0.5% | ʻO ND |
| ʻAʻole ʻoi aku ka EtAC ma mua o 0.5% | ʻO ND | |
| n-Heptane ʻaʻole ma mua o 0.5% | emi ma mua o 0.1% | |
| Koena ma ka hoʻā ʻana | emi ma mua o 0.2% | 0.10% |
| Nā metala kaumaha e like me Pb | ʻaʻole i ʻoi aku ma mua o 20ppm | emi ma mua o 20ppm |
| Assay (HPLC) | ʻaʻole emi ma lalo o 98.0% | 99,60% |
| Panina hopena | Kūpono i nā Koina | |
ʻO Orlistat kahi ʻano hou i ʻike ʻia ma waena o nā lāʻau lapaʻau hōʻemi kaumaha. ʻO Sainike kona inoa kalepa a kūʻai mua ʻia ma Nūhōlani i ka makahiki 1998. ʻO Orlistat kahi wā lōʻihi a me ka maikaʻi loa o ka gastrointestinal lipase inhibitor, a he hiki ʻole ke hoʻoheheʻe ʻia i ka wai, hiki ke hoʻoheheʻe ʻia i ka chloroform, a maʻalahi hoʻi i ka etanol.
Hiki ke hoʻohana ʻia ʻo Orlistat i ka lāʻau lapaʻau e mālama i ka momona. ʻO ka maʻamau, lawe ʻia kahi mahele o 120mg i ʻekolu mau manawa i ka lā ma loko o hoʻokahi hola o ka pāʻina ʻai. Hoʻomaka ka hōʻemi kaumaha ma hope o ʻelua mau pule o ka hoʻohana. Hiki ke hoʻohana mau ʻia no 6-12 mau mahina, a e pau nā hopena ma hope o ka nui o 400mg i kēlā me kēia lā. Kūpono kēia lāʻau e hoʻohana pū ʻia me ka papa ʻaina haʻahaʻa-calorie e nā poʻe momona a nui, a hiki ke hoʻohana ʻia ia i mea lapaʻau lōʻihi no nā mea maʻi i kū i nā pilikia pilikia e pili ana i ke kaumaha. Loaʻa iā Orlistat kahi hopena kaohi-lōʻihi e hoʻemi a mālama i ke kaumaha a pale i ka rebounding. Hiki i ka Orlistat ke hoʻohaʻahaʻa i nā hanana o nā pilikia a me nā maʻi e pili ana i ke kaupaona, e like me hypercholesterolemia, ʻano diabetes 2, hoʻowahāwahā ʻia i ka glucose, hyperinsulinemia, a me hypertension, a hiki iā ia ke hōʻemi i ka momona o nā kino. Hoʻoponopono ʻo Orlistat i nā pae lipid koko: hiki iā ia ke hoʻēmi i nā triglycerides serum (TG) a me ka lipoprotein kolesterol haʻahaʻa (LDL-C), a hiki ke hoʻonui i ka lākiō o nā lipoproteins kiʻekiʻena i nā lipoproteins haʻahaʻa i nā mea maʻi nui.
