Mai ka makahiki 2007, ʻo mākou kekahi o nā alakaʻika pauda orlistatmea hoʻolako mea hana ma Kina
ʻO Orlistat (CAS NO.96829-58-2) kahi lāʻau i hoʻolālā ʻia e mālama i ka momona.Hoʻohana nui ʻia ia no ka pale ʻana i ka absorption o nā momona mai ka ʻai kanaka, a laila e hōʻemi ana i ka ʻai caloric.Ma waho aʻe, ua manaʻo ʻia no ka hoʻohana pū ʻana me kahi meaʻai hoʻemi-calorie i mālama ʻia e ke kauka.
'ikamu | Nā koi | Nā hopena hoʻāʻo |
Ka nana aku | ʻoiai i ka pauka pauka | Pauda keʻokeʻo |
ʻIkepili | Ka manawa mālama HPLC | Kūlike |
Lae hehee | 42 ºC -45°C | 42°C-44°C |
ʻO ka hoʻololi ʻike ʻike | -31.0°~-41.0° | -36.0° |
Maemae e HPLC | ʻaʻole emi ma lalo o 98.0% | 98.5% |
Huina haumia | ʻaʻole ʻoi aku ma mua o 2.0% | 1.6% |
Max Ka haumia kanaka | ʻaʻole ʻoi aku ma mua o 0.5% | 0.3% |
Waiwai%(K&F) | ʻaʻole ʻoi aku ma mua o 0.5% | 0.1% |
Nā mea hoʻoheheʻe koena | ʻAʻole ʻoi aku ka nui o ka EtOH ma mua o 0.5% | ND |
ʻAʻole ʻoi aku ka nui o ka EtAC ma mua o 0.5% | ND | |
n-Heptane ʻaʻole ʻoi aku ma mua o 0.5% | emi ma lalo o 0.1% | |
Ke koena ma ka ʻā | emi ma lalo o 0.2% | 0.10% |
Nā metala kaumaha e like me Pb | ʻaʻole ʻoi aku ma mua o 20ppm | emi iho malalo o 20ppm |
ʻIke (HPLC) | ʻaʻole emi ma lalo o 98.0% | 99.60% |
Ka hopena | Kū i nā koi |
ʻO Orlistat kahi ʻano hou o ka lāʻau hoʻemi kaumaha i ʻike ʻia ma ka honua.ʻO Sainike kona inoa kālepa a kūʻai mua ʻia ma New Zealand i ka makahiki 1998. ʻO Orlistat kahi mea hoʻopaneʻe lipase gastrointestinal kūikawā no ka wā lōʻihi a maikaʻi loa, a ʻaʻole hiki ke hoʻoheheʻe ʻia i ka wai, hiki ke hoʻoheheʻe ʻia i ka chloroform, a maʻalahi hoʻi i ka ethanol.
Hiki ke hoʻohana ʻia ʻo Orlistat i ka lāʻau lapaʻau e mālama i ka momona.ʻO ka maʻamau, lawe ʻia kahi maʻi o 120mg i ʻekolu manawa i ka lā i loko o hoʻokahi hola o ka ʻai.Hoʻomaka ka pohō kaumaha ma hope o ʻelua pule o ka hoʻohana ʻana.Hiki ke hoʻohana mau ʻia no 6-12 mau mahina, a e pau kona hopena i ka hoʻonui ʻana ma hope o ka nui o kēlā me kēia lā ma mua o 400mg.He kūpono kēia lāʻau lapaʻau e hoʻohana pū me ka ʻai haʻahaʻa-calorie e ka poʻe paʻakikī a me ke kaumaha nui, a hiki ke hoʻohana ʻia e like me ka mālama lōʻihi no nā poʻe maʻi i kū i nā pilikia pili i ke kaumaha.Loaʻa i ka Orlistat kahi hopena hoʻomalu kaumaha lōʻihi e hōʻemi a mālama i ke kaumaha a pale i ka rebounding.ʻO ka hoʻohana ʻana iā Orlistat hiki ke hoʻohaʻahaʻa i nā hanana o nā mea pili i ke kaumaha a me nā maʻi, me ka hypercholesterolemia, type-2 diabetes, impaired glucose tolerance, hyperinsulinemia, a me ka hypertension, a hiki ke hoʻemi i ka momona momona i loko o nā kino.Hoʻoponopono pū ʻo Orlistat i nā pae lipid koko: hiki iā ia ke hoʻemi i ka triglycerides serum (TG) a me ka lipoprotein cholesterol haʻahaʻa (LDL-C), a hiki ke hoʻonui i ka ratio o nā lipoproteins kiʻekiʻe kiʻekiʻe i nā lipoproteins haʻahaʻa haʻahaʻa i nā maʻi obese.
Hebei Guanlang Biotechnology Co., Ltd. no Guanlang Group, i hoʻokumu ʻia i ka makahiki 2007, aia ma Shijiazhuang kūlanakauhale ʻo ia ke kapikala o Hebei Province a me ka ʻāpana hub ma waena o Beijing Tianjin a me Hebei a loaʻa iā ia ka pono o ka lawe ʻana.ʻO kā mākou hui kahi ʻoihana ʻenehana kiʻekiʻe hou me ka Research & Development, ka hana ʻana a me ke kūʻai aku.