Huahana: 2-phenylacetamide
Huina molekala: C8H9NO
Kaumaha molekula: 135.17
Ka inoa Pelekane: Phenylacetamide
ʻAno: Keʻokeʻo keʻokeʻo a i ʻole nā aniani lau.Mp 157-158 ℃, bp 280-290 ℃ (decomposition).Hiki ke hoʻoheheʻe ʻia i loko o ka wai wela a me ka ethanol, hiki ke hoʻoheheʻe ʻia i ka wai anuanu, etera, a me benzene.
Hoʻohana: ʻO waena o nā lāʻau lapaʻau e like me ka penicillin a me ka phenobarbital.Hoʻohana ʻia ia no ka hoʻomākaukau ʻana i ka waikawa phenylacetic, nā mea ʻala, a me nā pesticides.
Hana 1) Masuko F，Katsura T.US 4536599A1.1985.
E hoʻohui i 117.2 g (1.0 mol) o ka phenylacetonitrile (2), 56.1 g o 25% potassium hydroxide solution, 291.5 g o 35% hydrogen peroxide aqueous solution, 1.78 g benzyltriethylammonium chloride, a me 351.5 g o ka flask isopropanol.E hoʻoulu a hana i ka 50 ℃ no 4 mau hola.Ma hope o ka pau ʻana o ka hopena, hoʻoheheʻe ʻia ka isopropanol ma lalo o ke kaomi hoʻohaʻahaʻa, hoʻomaʻalili, kānana, holoi ʻia me ka wai, a maloʻo no ka loaʻa ʻana o ka pūhui (1) 128.5 g, mp 155 ℃, me ka hua o 95%.
Hana 2) Furniss BS，Hannaford AJ，Rogers V，et al.Vogel's Textbook of Practical Chemistry.Longman London and New York.Fourth edition，1978：518.
E hoʻohui i 100 g (0.85 mol) o ka phenylacetonitrile (2) a me 400 mL o ka waika hydrochloric concentrated i loko o ka pahu pane.Ma lalo o ka hoʻoulu ʻana, e hana i ka 40 ℃ no kahi o 40 mau minuke, a hoʻonui i ka mahana i 50 ℃.E hoʻomau i ka hana no 30 mau minuke.Hoʻolili i 15 ℃ a hoʻohui i 400 mL o ka wai hoʻoheheʻe anuanu.Hoʻomaʻalili i ka ʻauʻau wai hau, kānana ʻana i nā kristal.E hoʻohui i ka paʻa i 50 mL o ka wai a hoʻoulu maikaʻi e wehe i ka waikawa phenylacetic.E kānana a maloʻo ma 50-80 ℃ no ka loaʻa ʻana o 95 g phenylacetamide (1), mp 154-155 ℃, me ka hua o 82%.ʻO ka hana hou ʻana me ka ethanol, mp 156 ℃.
Ka manawa hoʻouna: Apr-11-2023